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Preventing Neovascularization from Contact Lenses

Preventing Neovascularization from Contact Lenses

Introduction

Corneal neovascularization is a serious eye condition that can result from improper contact lens use. Understanding its causes, recognizing the symptoms, and adopting preventive measures are crucial for maintaining good eye health. This article delves into the science behind neovascularization, its implications for contact lens wearers, and practical steps to prevent it.

What is Neovascularization?

Illustration of neovascularization in the eye, showing abnormal growth of blood vessels in the cornea, which can lead to vision impairment and permanent vision loss. The image highlights the choroidal neovascular membrane, a condition often caused by hypoxia and inflammation.

Neovascularization refers to the abnormal growth of new blood vessels in tissues where they are not typically present. This condition can lead to significant vision problems, as the new vessels can cause scarring and result in permanent vision loss. When the cornea, which is naturally avascular (without blood vessels), starts developing these new vessels, it is often a response to hypoxia (lack of oxygen) and inflammation. These new blood vessels can interfere with vision by clouding the cornea and causing vision impairment.

Illustration of corneal neovascularization showing an eye with red, inflamed blood vessels in the cornea, alongside a symbol indicating a lack of oxygen (O2). The image highlights the response of the cornea to hypoxia and inflammation, leading to the growth of abnormal blood vessels.

Understanding Corneal neovascularization

Definition and Mechanism: Corneal neovascularization occurs when the cornea, which is normally avascular, starts developing new blood vessels. This process is typically a response to hypoxia (lack of oxygen) and inflammation. The cornea requires oxygen to function properly, and when it doesn't get enough oxygen, the body compensates by growing new blood vessels to supply the needed oxygen.

Symptoms: Common symptoms include redness, discomfort, decreased vision, and the appearance of new, abnormal blood vessels in the cornea. Early detection of these symptoms is crucial to prevent further complications.

Causes of Corneal Neovascularization in Contact Lens Wearers

Close-up image of a person inserting a contact lens into their eye, illustrating the potential risks of prolonged contact lens wear, such as reduced oxygen supply to the cornea and the development of corneal neovascularization.

Prolonged Wear of Contact Lenses

Wearing contact lenses for extended periods, especially beyond the recommended duration, can significantly reduce the oxygen supply to the cornea, triggering neovascularization. Continuous wear of contact lenses prevents the cornea from getting the necessary oxygen from the air, leading to hypoxia and subsequent growth of new blood vessels.

Poor Lens Hygiene and Care Practices

Inadequate cleaning and disinfecting of contact lenses can lead to bacterial buildup and infections, contributing to inflammation and neovascularization. Proper lens hygiene is essential to prevent the accumulation of bacteria and debris on the lenses, which can cause infections and irritate the cornea. One day disposable contact lenses are another option to reduce bacterial buildup and reduce infection risk.

Close-up illustration of a contact lens with low oxygen permeability, highlighting the risk of hypoxia and neovascularization due to restricted oxygen flow to the cornea

Low Oxygen Permeability Lenses

Contact lenses with low oxygen permeability restrict the amount of oxygen that reaches the cornea, increasing the risk of hypoxia and subsequent neovascularization. Choosing high-oxygen permeability lenses can help in maintaining the health of the cornea by allowing more oxygen to reach the oxygen.

Illustration showing the impact of ill-fitting contact lenses on the eye, highlighting the importance of proper fit to prevent mechanical irritation and inflammation that can lead to abnormal blood vessel growth.

Ill-Fitting Contact Lenses

Lenses that do not fit properly can cause mechanical irritation to the cornea, leading to inflammation and promoting abnormal blood vessel growth. Ensuring that contact lenses are properly fitted by an eye care professional can prevent unnecessary friction and irritation.

Overwearing Contact Lenses

Using contact lenses beyond the recommended time period, especially disposable ones, can degrade the lens, causing discomfort and increasing the risk of complications like neovascularization. Adhering to the recommended replacement schedule for contact lenses is crucial for eye health.

Risks and Complications of Neovascularization

Corneal neovascularization can lead to severe complications if left untreated. Understanding these risks can emphasize the importance of preventive measures and early detection.

A person undergoing an eye examination using a specialized device to detect corneal neovascularization, highlighting the importance of early detection and treatment to prevent potential vision impairment.

Potential Vision Impairment

The new blood vessels can result in loss of corneal clarity, causing blurred vision and even permanent vision loss if the condition progresses. Early detection and treatment are essential to prevent irreversible vision loss.

Illustration of a person experiencing eye discomfort due to neovascularization, highlighting the increased risk of eye infections caused by the growth of new blood vessels in the cornea.

Increased Risk of Eye Infections

The presence of new blood vessels can facilitate the entry of pathogens into the cornea, increasing the likelihood of eye infections. Maintaining proper hygiene and regular eye check-ups can help in early detection and prevent infections.

Illustration of a patient undergoing an eye examination, highlighting the impact of corneal neovascularization on overall eye health, including chronic discomfort, redness, and irritation.

Impact on Overall Eye Health

Corneal neovascularization can cause chronic discomfort, redness, and irritation, affecting the overall health and comfort of the eyes. Managing the condition with appropriate treatment can improve the quality of life and prevent further complications.

Most cases of neovascularization can be prevented with regular eye exams and good contact lens hygiene," says Dr. David Jupiter.   It is essential to remove contact lenses from the eyes at the first signs of redness and/or discomfort.   Redness and eye discomfort are often signs that something is irritating the eyes. Contact lens wear can be the primary or a contributing source of the irritation and discomfort. Left unchecked, this can lead to significant inflammation.  

Preventive Measures for Neovascularization

Infographic showing preventive measures for neovascularization, including choosing high-oxygen permeability contact lenses, maintaining proper lens hygiene, following recommended wearing schedules, and scheduling regular eye examinations with an optometrist.

Choosing the Right Contact Lenses

Opt for high-oxygen permeability lenses to improve oxygen supply to the cornea. These lenses are designed to allow more oxygen to pass through to the cornea, reducing the risk of hypoxia.

Adhering to Proper Lens Hygiene

Maintaining strict hygiene practices can significantly reduce the risk of infections and neovascularization. Regular cleaning and disinfecting of contact lenses (or wearing one day disposable contact lenses) can significantly reduce bacterial buildup thereby reducing the risk of corneal complications.

Following Recommended Wearing Schedules

Avoid wearing contact lenses overnight or beyond the recommended duration to prevent hypoxia. Adhering to the prescribed wearing schedule can prevent unnecessary strain on the cornea.

Regular Eye Examinations

Regular check-ups with an optometrist can help detect early signs of neovascularization and other eye conditions. Early detection can lead to timely treatment and prevent further complications.

Treatment Options for Corneal Neovascularization

Collage showing different stages of treatment for corneal neovascularization, including an eye exam with an optometrist, surgical procedures performed by an eye surgeon, and the importance of early detection through regular eye exams.

If detected early, corneal neovascularization can be managed and treated effectively. Understanding the available treatment options can help in making informed decisions.

Medical Treatments

Treatments often include cessation of contact lens wear until the eye doctor feels it’s OK to resume wear, antibiotic eyedrops to reduce or eliminate infection, and steroidal anti-inflammatory eyedrops to resolve the inflammation.

Surgical Procedures

In severe cases, surgical interventions may be necessary to restore vision loss associated with contact lens related corneal damage. Consulting with an eye care professional can help to determine the best treatment plan.

Importance of Early Detection

Early detection through regular eye exams is crucial for successful treatment and preventing long-term complications. Regular monitoring and timely intervention can ensure the health of your eyes.


Preventing neovascularization from contact lenses involves a combination of choosing the right lenses, adhering to proper hygiene practices, and following recommended wearing schedules. Regular eye exams are essential for early detection and effective management of this condition. By taking these preventive measures, you can maintain healthy eyes and enjoy the benefits of contact lenses.

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Contributor

David Jupiter, O.D.

David Jupiter, O.D.

Dr. David Jupiter is a licensed optometrist based in Maryland, United States, with a career spanning over three decades in providing top notch eye care. His professional experience includes working...

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The information in this post and all EyeCandys blog content is intended for informational and marketing purposes only and should not be taken as medical advice. EyeCandys does not offer professional healthcare advice or practice medicine, optometry, or any other healthcare profession. Always consult with your ophthalmologist, optometrist or a qualified healthcare provider for any medical advice, diagnosis, treatment, or questions regarding a medical condition.

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